A big part of skin allergies is this: if you come into contact with an allergen on a daily basis, it's gonna getcha. Big time. My hands were getting DESTROYED and after noticing an area between my thumb and pointer finger, I realized that area was where my pens were resting while writing. Now, how in the H do you avoid pens?? Here's a quick fix:
Wrap it in masking tape! It's papery, so it works. I always keep a roll handy at my desk. I tape up plastic drawer handles too.